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Methionine is an essential amino acid obtained from dietary protein and serves as the starting point of the methylation cycle
BPC-157 is described as well tolerated and without demonstrated toxicity in rodents, but the human safety dossier is unpublished, and over 80 percent of the literature comes from a single research group, so independent replication is limited Sikiric et al., 2025
It is unknown whether the IGF-1 LR3 side effects can lead to the development of growth hormone deficiency or long-term health problems such as cardiovascular disease
Risks include standard surgical complications such as infection, bleeding, and scarring
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