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Vitamin B12 injections help with memory and mental focus and may help prevent early dementia
The risk of reduced potency or contamination is not worth the savings from squeezing out a few extra doses
In animal-model work, NNMT inhibition with 5-Amino-1MQ has been associated with changes in adipose-tissue mass, in NAD+ pool sizes (because NNMT consumes nicotinamide that would otherwise feed the NAD+ salvage pathway), and in methyl-donor dynamics (because NNMT consumes S-adenosylmethionine)
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