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Subcutaneous injections are generally less painful because fatty tissue has fewer nerve endings than muscle
Semaglutide (weight loss doses): At the 2.4mg dose (Wegovy), average loss reaches approximately 15%
In their separate Phase 2 trials, retatrutide monotherapy showed larger weight loss (~24.2% at 48 weeks, 12 mg) than standalone cagrilintide (~10.8% at 26 weeks, 4.5 mg), and indirect network meta-analyses rank retatrutide highly
Common ones include nausea, yawning, facial flushing, leg aches, pins and needles , and in some males, spontaneous erections
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