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Some protocols call for a one-month break every two months of use
Anesthesia is typically not required for most filler treatments unless specifically requested by the patient or recommended by the practitioner for specific circumstances
doi:10.3390/ani14101462
Various mediators, including inflammatory cytokines and prostaglandins, can affect paracellular TJs and vesicular transport in ECs and are involved in multiple mechanisms (133, 134)
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