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Young males displayed also higher NADP + /NADPH ratio in frozen blood compared to age-matched females, while NADH and GSSG were higher and GSH/GSSG ratio lower in 31-40 years old males compared to females (Supplementary figure 2i-s)
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Group III (Treated group) was further sub-classified into HCC patients treated with sorafenib 40 patients (Sor group, 29 male and 11 female) with a mean age of 65.54 0.89 years and HCC patients treated with regorafenib 40 patients (Rog group, 30 males, 10 female) with a mean age of 60.24 1.57 years
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