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Compared to Phentermine/Topiramate, Tirzepatide showed an observed association with reduced incidence only for dry eye disease (HR 0.29, 95% CI: 0.150.57, p = 1.3 10 4 ), with other outcomes showing non-significant trends, including cataracts (HR 0.76, 95% CI: 0.381.52, p = 0.433)

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