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This paper systematically reviews the regulation of GA metabolism and immune responses in the hyperuricemia occurring due to FA metabolic disorders and identifies targets for personalized therapy based on the underlying mechanisms ( Disordered FA metabolism further promotes inflammation, and elevation of the uric acid levels, primarily through high levels of FAs, activates the initiation of inflammation

Of note, location of the proximal catheter in the ventricle or lumbar subarachnoid space was not significantly associated with admission or shunt revision in the multivariable analyses

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That 2.6 percentage-point gap between 1.0 mg and 2.4 mg represents a meaningful clinical difference, roughly 6 to 7 additional pounds for a 250-pound patient