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Tamoxifen injection in adult mice to activate the Cre system avoids the effects of EGFR deletion on embryological development that occur with the insulin promoter driving cre, without an ERT, and specifically -cell development and maturation
From there youll monitor appetite, body weight, blood sugar, side-effects, and your provider will determine when (and whether) to increase the dose to improve blood sugar control
22 : 857871 Hibbeln JR, Palmer JW, Davis JM
We don't fully understand the weight loss-independent mechanisms through which GLP-1 reduces inflammation is it through the brain, or via T cells, or other pathways
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