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Common side effects include nausea, vomiting, and gastrointestinal discomfort, particularly during dose escalation

Nicotinamide N-methyltransferase (NNMT) inhibition increases energy expenditure and decreases fat storage, two important aspects of treating insulin resistance, a defining feature of type 2 diabetes

A normal response to the stimulus was first determined in the unoperated left hind limb and was defined as an immediate withdrawal of the limb with or without a vocalization

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