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Fatty acid oxidation-induced HIF-1 activation facilitates hepatic urate synthesis through upregulating NT5C2 and XDH
In view of the pivotal role played by GSH in redox system and the relationship between oxidative stress and autophagy 68 , it is conceivable that GSH depletion-induced oxidative stress and lipid peroxidation may be a key point linking ferroptosis and autophagy in RPE cells
Ethics declarations The authors declare no conflicts of interest
Like B12 shots, oral supplements are generally safe (4), even if you take more than the recommended 2.4 pg/mL per day
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