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1 Introduction Migraine manifests as a chronic neurovascular disease characterized by unilateral or bilateral throbbing severe headaches, predominantly unilateral, recurring with symptoms such as nausea, vomiting, photophobia, and phonophobia that impair autonomic nervous system functions ( Migraine is a multifactorial disorder closely related to oxidative stress and neurogenic inflammation

5.4.3 Dihydromyricetin Dihydromyricetin (DHM), the main flavonoid in rattan tea, exhibits broad pharmacological effects, including cardioprotection, anti-diabetes, hepatoprotection, neuroprotection, and anti-tumor activity

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Presented for research literature review only Wildenburg G et al