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Your cells become more efficient at using stored fat for fuel (ketosis-like state), and your appetite regulation stabilizes at a new baseline

Eur J Neurosci 57(1):148162 Daniele G, Iozzo P, Molina-Carrion M et al (2015) Exenatide regulates cerebral glucose metabolism in brain areas associated with glucose homeostasis and reward system

When to reduce dose or stop Reduce your dose if side effects are persistent (lasting more than a few days), interfere with daily activities, or worsen rather than improve over time