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At clinical concentrations, pretomanid does not inhibit major CYP isoenzymes, including CYP1A2, CYP2C8, CYP2C9, CYP2C19 or CYP2D6, and does not induce CYP2C9 or CYP3A4, limiting the potential for DDI trough CYPs

Mobilising fatty acids improves endurance, enabling longer training sessions and greater fat burn

Other potential benefits include enhanced blood-glucose management, improvements in cardiovascular health, reductions in inflammation, and possibly even liver support for those with non-alcoholic fatty liver disease