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A randomized trial for the treatment of refractory status epilepticus
Clues that laxity may be the main driver include: Crepey or loose skin under the chin Prominent platysmal banding (vertical neck bands) A turkey neck appearance rather than a soft fat pad Jowling related to tissue descent rather than fatty fullness If weight-related fat is the main factor For some patients, submental fullness is part of overall weight distribution
Tailoring protocols to specific study goals enhances research relevance and outcome quality
Studies have shown that PDEVs can exert hepatoprotective, anti-inflammatory effects in models of liver injury
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