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Reported effects May promote deeper, more restorative slow-wave sleep Could improve subjective sleep quality Potential for stress-protective and anxiolytic-like effects Studies suggest no pharmacological tolerance development Reported side effects Generally well tolerated in human studies Occasional mild injection-site reactions may occur Limited long-term safety data

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Third, we identified distinct patient phenotypes with markedly different treatment responses, enabling practical applications in the clinic

123,124 The recent phenomenon has therapeutic implications related to asthma by preventing proliferation and remodeling of smooth muscle cells