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10.1186/s12974-018-1289-z 29 ChengX
Carnitine has a trophic genomic effect, inducing the protein activity and mRNA expression of a variety of nuclear receptors, directly regulating nuclear receptor signaling to affect downstream targets of cell metabolism [32]
Although patients receiving exenatide IR and experiencing longer durations of nausea and vomiting tended to lose more weight, those in the trial group who did not experience the gastrointestinal symptoms (70%) generally lost weight as well (166, 224)
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