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GLP-1 Side Effects While GLP-1 drug therapy is generally safe, some patients may experience mild side effects such as: Nausea Vomiting Diarrhea Constipation Headache Fatigue Most side effects lessen with time as the body adjusts

Some lean mass loss can occur during weight loss regardless of the method used

The Kidney Disease Improving Global Outcomes 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease recommends adults with CKD and either an eGFR 20 mL/min/1.73 m 2 or higher plus UACR of 200 mg/g or higher, or those with heart failure, receive SGLT2 inhibitor therapy

Among AOMs, tirzepatide is the most prescribed AOM medication