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& Giovannucci, E
Comparison with the binding modes of other dual and triple agonists highlight that the N-terminal and C-terminal regions of the peptide confer receptor selectivity, whereas the middle region offers opportunities for sequence optimization to refine receptor engagement, thereby presenting a useful template for designing better unimolecular therapeutics
Lycopene attenuates tulathromycin and diclofenac sodium-induced cardiotoxicity in mice
Demonstrated this in a 1998 study showing that ipamorelin released GH in a dose-dependent manner in swine without elevating cortisol or prolactin at doses up to 1 mg/kg [1]
