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As an example, GSH depletion has been shown to promote pro-inflammatory microglial phenotypes and amplify astrocyte-microglia crosstalk (Vilhardt et al., 2017)
A simpler protocol with 80% effectiveness that you follow consistently will always outperform a complex protocol with 100% theoretical effectiveness that you abandon after two months
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But when the mitochondria make energy, they also make reactive oxygen species (ROS), substances that can damage mitochondria and your cells, unless they are neutralized by antioxidants like glutathione 13
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