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Mir Ali, a bariatric surgeon at Orange Coast Medical Center, explains: "Consuming a high amount of calories can still lead to weight gain or a plateau, even on these medications
Further, MT-I and MT-II do not possess any anabolic properties or affinity to the same receptors as steroids and are not controlled substances
In fact, a case of rapid onset diabetic ketoacidosis has been reported after addition of the SGLT2 inhibitor empaglflozin to metformin, sitagliptin and gliclazide in a patient with unrecognized acromegaly and type 2 diabetes (54)
doi: 10.1105/tpc.113.111815
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