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Additionally, some medications reduce glutathione levels by being substrates for conjugation
Treatment for MASH is considered indicated when there is a score 4 in the Non-Alcoholic Steatohepatitis (NASH) Clinical Research Network (NASH CRN) histological scoring system, or an activity score 2 according to the Steatosis, Activity, and Fibrosis (SAF) scoring system, together with significant fibrosis 9,10
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Post-guideline, metformin prescriptions dropped to 68.5%, while semaglutide prescriptions rose to 20% for patients receiving a prescription
Selection should depend on donor characteristics, scalp laxity, graft requirements, hairstyle and scarring preferences, previous surgery, long-term donor planning and the surgeons competence
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