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25 In a later study, it was shown that in vitro treatment of whole blood cultures from HIV+ subjects with N-acetyl cysteine (NAC), a GSH precursor, resulted in improved control of intracellular M
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Elevated ROS levels, especially in the early stages of cancer, can contribute to carcinogenesis by promoting genomic instability, mitogenic signaling pathways, and the NF-B pathway, among others [26]
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