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Signs you might accelerate the titration In limited cases, your provider may shorten the time at a given dose level to 2-3 weeks instead of 4 if: You experience zero GI side effects at the current dose Appetite suppression is minimal (you are eating nearly the same as before) You have prior experience with GLP-1 agonists and demonstrated good tolerance Weight loss is below 0.5% per week at the current dose for 3+ weeks Accelerated titration should only be done under professional guidance

There is no reason to start at anything but the lowest dose