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Recent pharmaceutical research is focusing on advanced drug delivery systems to overcome these limitations

(2016): Potential Intervention of alpha- Lipoic Acid and Carnitine on Insulin Sensitivity and Anti-Inflammatory Cytokines Levels in Fructose-Fed Rats, a Model of Metabolic Syndrome

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Synthesis of D-P H-His(Trt)-OMeHCl (5.0 g, 11.15 mmol), Boc-Gly-OH (2.15 g, 12.25 mmol), HATU (8.5 g, 22.35 mmol) and HOAT (3.0 g, 22.35 mmol) were dissolved in DMF (80 mL) under nitrogen atmosphere and ice bath conditions