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7 Endocrine Therapy Interaction: The MD Anderson Cancer Center retrospective observational cohort study also found tamoxifen or aromatase inhibitor (AI) use is typically associated with weight gain of +2.3 kg ( P = .037)

Signs that medical advice is needed include: Persistent irritability that does not improve with lifestyle changes Feelings of anxiety, depression, or extreme mood swings Sudden changes in behavior or emotions Severe digestive issues that make it difficult to eat or function normally Doctors may adjust the dosage, suggest dietary changes, or recommend additional strategies to improve well-being

Community subcutaneous research plans often reference 300-500 mcg per day

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