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Rather, it focused on specifically determining the cardiovascular superiority of dulaglutide relative to cardiovascular endpoints
Approximately 57% of patients experienced decrease in appetite, which was consistent across the PIONEER trials [35,36,37,38,39,40,41,42,43,44]
Mechanistic rationale, early observations, and emerging data can all contribute to discovery, but the translational challenge is understanding when those signals can be interpreted with enough confidence to support a medical decision
The cleanest way to hold the difference in mind is to count hormonal axes and ask what each does to the energy-balance equation
