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All protocols described here are based on animal studies or limited clinical data and are presented for educational purposes
Immune activation and mitochondrial dysfunction in both central and peripheral immune cells (like microglia in the brain and monocytes in blood) are implicated in these cognitive complications ( 4.2.1 Neuroinflammation after surgery Surgical trauma induces a rise in pro-inflammatory cytokines (IL-6, TNF-) that can cross the blood-brain barrier or signal via vagal pathways to activate brain endothelium and microglia (128, 129)
"The Council's Pharmaceutical Needs Assessment for 2025-2028 did not identify any gaps in the provision of necessary pharmaceutical services and concluded that the current network of pharmaceutical providers is expected to be sufficient to meet local needs during the life of the assessment
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