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Across preclinical studies, Epitalon has shown: Telomerase activation and telomere extension: Via TRAP assays and fibroblast lifespan extension beyond the Hayflick limit Epigenetic remodeling: Reversal of chromatin aging, histone modulation, and gene promoter binding Redox homeostasis: Increased antioxidant enzymes (SOD, NQO1, catalase) and reduced ROS, lipid peroxidation, and DNA damage Circadian restoration: Upregulation of AANAT/pCREB, normalized melatonin and cortisol rhythms, and clock gene modulation in humans Cancer risk reduction: Reduced tumor multiplicity and delayed onset in HER-2/neu and colon cancer models
Winner: Sermorelin takes the affordability crown at $150-200 monthly for standard dosing
Some of these claims have clinical grounding, while others stretch the evidence considerably
Catalases are involved in antioxidant defense mechanism have been enunciated in many studies [127, 128, 129, 130, 131, 132]
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