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Six participants were included in the ITT but excluded from the per-protocol (PP) analysis because they did not satisfy the definition of full adherence and therefore did not meet the conditions to be included in PP analysis

2020) reported that, although parameters such as particle size and PEGylation influence nanoparticle cellular uptake, these characteristics exert only a limited effect on their overall translocation to the central nervous system

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Signs of Allergic Reaction : If you notice symptoms like difficulty breathing, swelling of the face or throat, or a severe rash, seek emergency medical attention immediately