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Supplements claiming "GLP-1" effects typically contain ingredients purported to stimulate the body's natural GLP-1 production or mimic its effects

The product reviewed here is not an approved human drug, dietary supplement, or treatment

Finally, following recent concerns by regulatory agencies regarding a potential increase in suicidal behavior associated with GLP-1RAs 206 , we found 1 recent pharmacovigilance report showing 0.6% suicidal events among 41,236 safety reports for these medications 207 and an emulated target trial of 86,418 older adults with T2DM that did not identify any difference in suicidal ideation or behavior between GLP-1RAs and other antidiabetic medications over 1.5 years 208

This is particularly beneficial within a balanced diet and regular exercise program