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This pharmacokinetic behavior supports the titration-based dosing strategies used in the ATTAIN and ACHIEVE trials, where the starting dose is low and gradually increased over several weeks to the target maintenance dose
Virulence attenuation of Streptococcus pneumoniae clpP mutant by sensitivity to oxidative stress in macrophages via an NO-mediated pathway
System X-c(-)/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy
Lazic D, Sagare AP, Nikolakopoulou AM, Griffin JH, Vassar R, Zlokovic BV
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