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Several other studies (one of them being a large scale community-based Framingham Heart Study [221]) have suggested a role for IGF-1 in the prevalence of insulin resistance and MetS [221223]
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This prevents potential local interactions and makes it easier to identify the source of any injection site reactions
Following the intake of nutrients, the beginning of the incretin effect is marked by rising levels of active GLP-1 which promote the synthesis and release of insulin 1,2,4
