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Induction of acute hepatotoxicity by acetaminophen overdose To test the efficacy of ABT in cytochrome P450 enzyme activity inhibition, we used the acetaminophen (APAP) model in mice, a standard approach where hepatotoxicity is mediated by cytochrome P450 enzymes (Schneider et al
doi: 10.1016/j.autneu.2003.11.001 163 VahlTPTauchiMDurlerTSElfersEEFernandesTMBitnerRDet al
doi:10.1002/jnr.23335
protocol shows why short trials are easy to misread
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