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Patients on Long-Term Medication: Certain medications, including metformin (for diabetes) and proton pump inhibitors (for acid reflux), can reduce B12 absorption over time
A 2025 head-to-head study confirmed it: tirzepatide users lost 20.2% vs 13.7% for semaglutide
Though not so common, some people develop allergic reactions from aerobic exercise such as jogging, or even less intense physical activity, such as walking
Only testing can tell you the answer, but a daily B12 injection schedule should be your starting point
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