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In addition to providing coverage of these drugs for obesity, which would be a new indication in Medicare and in most states under Medicaid, these efforts will also allow beneficiaries in participating states and Part D plans to access GLP-1s for obesity at a lower out-of-pocket cost than if they were to purchase them with cash at the direct-to-consumer prices offered by the manufacturers

A higher risk of diabetic retinopathy (DR) associated with semaglutide OW versus placebo was reported in SUSTAIN 6, although this increased risk of DR AEs with semaglutide OW versus comparators was not observed in SUSTAIN 1 to 5 or Japanese trials [58]