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Patients in the semaglutide or tirzepatide group had an increased incidence of other optic disc disorders, but this difference was not statistically significant (Figure 2)

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If PIM1 regulates NRF2, and persister cancer cells are dependent on glutathione 4 peroxidase (GPX4) and methionine extra-supply (transsulfuration pathway), then PIM1 inhibition might serve as a relevant therapeutic strategy

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