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Anthracyclines are another drug in the ALL regimen, which is associated with cardiotoxicity that is partially mediated by oxidative stress
doi: 10.1093/AJCN/88.1.167 267 SordilloJERifas-ShimanSLSwitkowskiKCoullBGibsonHRiceMet al
Reconstituting a 10mg vial with the water volume intended for a 5mg vial doubles your concentration and every dose that follows
If further testing continues to support the utility of these biomarkers to identify hepatotoxicity in other drugs besides acetaminophen in nonclinical species and in humans, the concept of biomarker qualification could be pursued for regulatory utility (US 2010)
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