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Systematic rotation of injection sites is important for preventing tissue changes and localized inflammation that can cause discomfort

Financial support for this research, including the article processing charge (APC), was obtained and received by J.L

Independent analyses of topically marketed products found none listed a prescription GLP-1 medicine as an active ingredient, so the branding rarely matches the contents inside the actual patch

Over-the-counter antidiarrheal medications like loperamide can be used judiciously for diarrhea (avoiding use if fever, blood in stool, or infection is suspected), though patients should consult their healthcare provider before regular use