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Mechanisms and strategies for combating cancer drug response and resistance Altered drug transport and metabolism One of the central barriers to effective chemotherapy is the development of MDR, wherein tumor cells acquire cross-resistance to structurally and mechanistically distinct agents (Fig
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Glucagon receptor: boosts fat metabolism and energy expenditure
The etiology and pathogenesis of ASD mainly include genetic mutations and chromosomal structural variations, inflammatory responses and oxidative stress, immune dysfunction, and neurotransmitter imbalances (4, 5)
