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Due to massive and persistent cultural and patient resistance and restrictive regulations, opioid-based OUD treatments like methadone and buprenorphine are used by a small fraction of people who could benefit from them

Yes not because of the medication itself, but because undernutrition is a real and often overlooked risk factor

H.LeeD.et al

Not only are there currently millions of people on these compounded drugs, all of whom would have to get new prescriptions to switch over to brand-name ones, but the market is ever-growing as these drugs gain new approved uses, like sleep apnea