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As of the October 2024 multisociety guidance led by the American Society of Anesthesiologists, the decision to stop Zepbound (tirzepatide) before surgery is individualized rather than automatic
Researchers planning crossover protocols must account for both plasma clearance (2448 hours) and functional washout (7296 hours minimum)
It is rare, but it has been documented in tirzepatide users, making awareness essential
The primary goals were to lower blood sugar levels and reduce the risk of diabetes-related complications
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