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For topical formulations, concentrations of 0.1 to 0.3 percent are used, with efficacy detectable from as low as 0.01 percent
In humans, the rate of taurine synthesis from methionine and cysteine is exceedingly low in comparison with rats (Sturman 1993), because the activity of hepatic cysteinesulfinate decarboxylase (a key enzyme in taurine synthesis) is about three orders of magnitude lower in the young and adult men than that in rats (Sturman and Hayes 1980)
Nelson Textbook of Pediatrics (20th ed.)
Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.26930(July 1994),1937519379,0021-9258 29
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