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For information about supplements that may help with other forms of nerve pain, see our answer to the question: Do any supplements, like Nervive, help with nerve pain, like sciatica or diabetic neuropathy
BPC-157 has been shown to upregulate epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), fibroblast growth factor-2 (FGF-2), and nerve growth factor (NGF) expression in multiple rodent tissue models
Even those taking supplements may require shots based on testing
A physician investigating unexplained hypercobalaminemia will typically order some combination of the following: Complete blood count (CBC) with differential to check for abnormal red blood cell, white blood cell, or platelet counts Liver function tests (ALT, AST, ALP, bilirubin, albumin) to assess liver health Kidney function tests (creatinine, BUN, estimated GFR) to evaluate renal clearance Peripheral blood smear if a myeloproliferative disorder is suspected Abdominal imaging (ultrasound or CT) if liver or abdominal pathology is a concern Cancer-specific markers or screenings if clinical suspicion warrants them The NIH Office of Dietary Supplements fact sheet notes that observational data from a Danish registry analysis of 757,185 people found the adjusted 1-year cancer risk was 1.74 to 4.72 times higher among those with B12 above 813 pg/mL compared to those in the normal range of 203 to 813 pg/mL
