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One of the primary reactions of methylcobalamin in the body is to convert homocysteine to methionine high homocysteine levels are undesirable and known to be an indicator of heart disease and stroke risk due to the fact free homocysteine in the blood causes sclerosis of the arteries, putting strain on the vascular system and the heart
Additionally, the rise of research-grade peptides from grey markets without verifiable information has only increased risk
It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years
Vitamin B12 deficiency is common
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