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Furthermore, AMPK activation phosphorylates MFF, which recruits DRP1 to the OMM, mediating mitochondrial fission and mitophagy

2019 Oct;30(10):745-755

Additionally, in a Phase II clinical trial targeting a population with Metabolism-Associated Steatohepatitis (MASLD), treatment with 2.4 mg of pemvidutide for 24 weeks resulted in a relative liver fat content reduction of up to 76% as opposed to the placebo group's 14%