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Nat Med 27:10791087
Individual speakers at a 2024 National Academies workshop suggested that GLP-1R agonists may reach the brain mainly through specialised uptake at the circumventricular organs, regions that sit outside the standard barrier, rather than by penetrating it
Rodents have a much higher density of GLP-1 receptors on thyroid C-cells compared to humans, making them more susceptible to C-cell proliferation
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