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On safety the article draws no meaningful distinction between them

The FDA-approved label defines the sequence and its minimum intervals so that the body is introduced to the medication gradually and consistently across patients, which is part of how tolerability is managed at the population level

Sympathoexcitation by central ANG II: roles for AT1 receptor upregulation and NAD(P)H [PMID: 15637113] Laboratory literature summary: Sympathoexcitation by central ANG II: roles for AT1 receptor upregulation and NAD(P)H oxidase in RVLM

However they also show differences in the overall fold with the presence of a DsbA-like domain inserted within the N-terminal thioredoxin-like domain 6