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Both classes of agents reduce cardiometabolic risk factors such as HbA1c, body weight, blood pressure and albuminuria, although the effects of GLP-1 receptor agonists on glycemia and body weight are substantially greater than those of SGLT2 inhibitors

Understanding how tirzepatide can affect menstrual and reproductive health provides broader context for these changes

Most private providers follow criteria broadly aligned with NICE guidance: A BMI of 30 or above , or A BMI of 37 or above alongside a weight-related comorbidity such as type 2 diabetes, hypertension, or obstructive sleep apnoea Some providers may consider patients with a BMI slightly below these thresholds at clinical discretion

Ballgown bridges the gap between transcriptome assembly and expression analysis