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Despite normalization of plasma homocysteine concentration, administration of folic acid, vitamin B 6 , and vitamin B 12 for 6 months was insufficient to restore normal vascular function in monkeys maintained for 17 months on an atherosclerotic diet that produced both hypercholesterolemia and hyperhomocysteinemia (Lentz et al, 1997)
EU/UK GMP Annex 13
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Fraxel Laser Cons Laser treatments are often not advisable for those with darker skin, as it has a higher risk of causing persistent hypopigmentation as well as temporary post-inflammatory hyperpigmentation
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