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The most pronounced inhibitory effects were observed at concentrations of 10 and 100 nM for each compound
Multi-Pathway ECM Remodeling Anti-Inflammatory Mechanism of Action Primary GHK-Cu: TGF- / LOX / Gene Expression ECM Remodeling & Gene Expression Modulation GHK-Cu (50mg) upregulates collagen synthesis, activates lysyl oxidase, and modulates over 4,048 genes identified by Connectivity Map analysis
T2DM is characterized by the presence of chronic fluctuating hyperglycemia, obesity-associated insulin resistance as well as the impaired secretion of insulin and dysfunction of the incretin system
Cancer 114 (11), 12271234
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